Pemetrexed mesothelioma

Pemetrexed mesothelioma
Mesothelioma patients may benefit from pemetrexed-based treatment.Many researchers are testing pemetrexed-based drugs as a second-line treatment option for mesothelioma relapse.
Mesothelioma is a rare cancer of lung lining and lining of other abdominal cavities. It is caused due to exposure to asbestos fibers. There are about 2000-3000 reported cases in USA only for Mesothelioma. There are many unreported cases of Mesothelioma in many developing countries.
Researchers have found that pemetrexed drugs benefited mesothelioma patients.
Few people were given pemetrexed-based drugs alone and few were given combination of pemetrexed-based and the current standard platinum-based drugs as part of research and treatment and almost half of the patients tested showed shrunken tumors or tumors that had stopped growing.Patients who responded well to pemetrexed-based drugs as a first-line treatment benefited from the same type second-line treatments.
Pemetrexed is a novel antifolate, a class of drugs that targets the folic acid metabolic pathway, which effects availability of certain B complex vitamins.
There are some side effects also which includes blood cell abnormalities, nausea and diarrhea
Researchers have reported results showing that patients on a new chemotherapy drug regimen live longer and have less pain than those on an older drug.
Pemetrexed is a novel antifolate, a class of drugs that targets the folic acid metabolic pathway, which effects availability of certain B complex vitamins.
The result showed that tumors shrank  in 41 percent of patients onpemetrexed in combination with a more commonly used chemotherapy agent called cisplatin.
Malignant pleural mesothelioma is associated with a history of asbestos exposure in about 70 to 80 percent of all cases and there is no approved or very effective chemotherapy for the disease.
Under the current expanded access program, Alimta may be available free to patients who qualify. Additionally, patients with mesothelioma may be entitled to large settlements against employers or asbestos makers.

Article publié pour la première fois le 17/03/2013

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