Stroke education Blood brings oxygen and nutrients to brain cells. stroke occurs when blood flow is interrupted to part of the brain. Without blood, brain cells quickly begin to die. it is estimated that the brain is deprived of oxygen, 32,000 brain cells die in every second.. stroke effect people in different ways. Greater the area of brain affected ,greater will be the extent of functional disability. Stroke is the number one cause of serious permanent disability. Disabilities commonly caused by stroke . 1) decreased or loss of sensation 2)partial or complete paralysis (hemiplegia) 3) loss of bowel and bladder control 4)difficulty in walking and problems with coordination and balance (ataxia) 5)visual disturbances 6)sexual ability is decreased 7)loss of balance 8)loss or decreased muscle tone 9)spasticity(increase in muscle tone) 10)central pain syndrome (thalamic pain) 11) difficulty in speech and understanding language (aphasia) 12)shortened retention spans and difficulty learning new information 13)inability or difficulty with swallowing(dysphagia) 14) impaired ability to do calculations or to organize, reason, and analyze 15)loss of short-term memory 16) Behavioural changes are common, such as lack of concern about situations, impulsivity, inappropriateness, and depression 17)coma 18)death can also occur Emotional disturbances are also common in stroke. It can cause lack of control emotions and an improper response This is called the pseudo bulbar affect (PBA). PBA is also known as emotional liability, which is a neurological disorder that causes sudden and unpredictable episodes of crying, laughing, or other emotional displays. Every 45 seconds someone suffers a stroke. Stroke kills nearly 160,000 people each year. Stroke is the third leading cause of death in this country. individuals who generally affected from stroke are under 65 years of age. men affected more as compared to women and blacks almost twice more often than whites. Stroke is the third- leading cause of serious, long-term disability. A stroke occurs when a blood vessel (artery) that supplies blood to the brain leaks, bursts or is blocked by a blood clot. Within an hour, the nerve cells in that area of the brain become damaged and may die. As a result, the part of the body controlled by the damaged area of the brain cannot work properly. Stroke requires immediate treatment. The sooner treatment is received, the better the chances of survival. . Thrombolytic therapy is the use of drugs to break the clot that is the main cause of stroke. patients who come to hospital within 3 hrs of the first sign of a stroke occur they have the possibility to receive Tissue Plasminogen Activator (tPA). There are many factors that determine whether or not a patient is able to receive thrombolytic therapy. Mostly it depends upon the amount of time between the onset of symptoms and presentation to the hospital.