Is It Necessary To Take Metformin Before And During Pregnancy
There are many women use metformin to cure PCOS. But they don’t know metformin probably cause birth defects. We need to discuss whether it is necessary to take metformin before and during pregnancy.
When you get pregnant, it is important to keep blood sugar in reasonable levels. A moderate blood sugar level can reduce the opportunities of birth defects and other complications. Generally, it is widely recommended that pregnant women take insulin to control blood sugar. But, sometimes they take metformin to gain more control on blood sugar level; especially when they have diabetes, using insulin alone cannot guarantee a reasonable blood sugar level. If you become pregnant while using metformin, you should not stop your medication without first talking to your physician.
If you are using metformin to cure PCOS, please do not stop this medication without any reference to your doctors when you want to get pregnant. It is because some researchers find that those people who has PCOS and use metformin have more opportunities of conception. And those people who got pregnant and still taking metformin at first three months have less opportunities of miscarriage. Also, small studies have shown that continuing metformin throughout pregnancy may decrease the likelihood of developing gestational diabetes. Depending on your medical history, your physician might encourage you to continue your medication during pregnancy or to stop it when you learn you’re pregnant. It is best to discuss these issues with your physician before getting pregnant.
As far as we know, few studies find that there is a direct connection between metformin and probability of birth defects. And some medical experiments find there is a certain connection between taking metformin in first three months after got pregnant and opportunities of birth defects. However, it is not clear whether these were caused by metformin or poor control of the mothers’diabetes. More recent trials studying the safety of metformin during pregnancy, mostly when used to treat insulin resistance in women with PCOS, did not show an increased rate of birth defects or complications at birth.
It is appropriate to use metformin to treat gestational diabetes after you got pregnant. Until now, there is no study demonstrating those women taking metformin to cure gestational diabetes after getting pregnant are more at risk of birth defects than other women. Therefore, metformin use during the second or third trimesters is not expected to increase the risk of complications for newborns.
Those women taking metformin have a thought that it could have bad effect on baby. But there is no research demonstrating obviously it has bad effect on baby. Although one research found there is a connection beween metformin and hypertension, later research denied its validity. A few researches have certified that taking metformin don’t bring more bad effects on babies than not taking it. There have been some reports of jaundice in babies exposed to metformin during pregnancy, but these reports do not prove that metformin was the cause of the jaundice. One study looked at the outcome of pregnancy after treatment of PCOS with metformin throughout pregnancy. Infants were found to have normal birth weight and height. At 6 months of age, these infants had normal weight, height, and social and motor development.
Article publié pour la première fois le 16/09/2016